Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.40 |
| ▸ | F2 | P00734 | 3/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LOX | P28300 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5900557 | 0.99 | F10 (0.47) | F10MAPK14CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL8267222 | 0.92 | F10 (0.58) | F10MAPK14CYP3A4HTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5901060 | 0.91 | F10 (0.49) | F10HTTSMN1; SMN2ST14F2 | |
| Hydrochloric Acid SCHEMBL5900730 | 0.91 | F10 (0.57) | F10MAPK14CYP3A4HTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5900704 | 0.90 | F10 (0.49) | F10ST14F2PRSS1PRSS2 | |
| SCHEMBL8265742 | 0.90 | HTT (0.49) | F10HTTSMN1; SMN2PTGER1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5900676 | 0.89 | HTT (0.49) | F10HTTSMN1; SMN2PTGER1ALDH1A1 | |
| SCHEMBL8266229 | 0.89 | F10 (0.52) | F10ST14F2PRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL5900575 | 0.89 | F10 (0.47) | F10ST14F2PRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL5177126 | 0.88 | F10 (0.51) | F10ST14F2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006027135-A1 | 4-AMINOMETHYL BENZAMIDINE DERIVATIVES AND THEIR USE AS FACTOR VIIIA INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-03-16 | — | — | WO | disclosed |