Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.35 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5086309 | 0.88 | F10 (0.41) | F10MAPTHTTKMT2AROCK2 | |
| Hydrochloric Acid SCHEMBL5178223 | 0.88 | F10 (0.53) | F10HTTKMT2AROCK2ROCK1 | |
| SCHEMBL5089129 | 0.84 | F10 (0.44) | F10HTTKMT2AROCK2ROCK1 | |
| SCHEMBL5186033 | 0.82 | HTT (0.41) | F10HTTKMT2AROCK2ROCK1 | |
| SCHEMBL8266479 | 0.79 | F10 (0.48) | F10ROCK2ROCK1EPHX2KLKB1 | |
| SCHEMBL8264808 | 0.78 | F10 (0.57) | F10HTTKMT2AROCK2ROCK1 | |
| Hydrochloric Acid SCHEMBL5900754 | 0.77 | F10 (0.56) | F10HTTKMT2AROCK2ROCK1 | |
| Acetic Acid SCHEMBL5178953 | 0.77 | F10 (0.48) | F10MAPTEPHX2AKR1B1KLKB1 | |
| SCHEMBL5176685 | 0.75 | EPHX2 (0.41) | F10ROCK2ROCK1EPHX2AKR1B1 | |
| SCHEMBL8265923 | 0.74 | F10 (0.63) | F10HTTKMT2AROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006027135-A1 | 4-AMINOMETHYL BENZAMIDINE DERIVATIVES AND THEIR USE AS FACTOR VIIIA INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-03-16 | — | — | WO | disclosed |