Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.51 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8265744 | 0.94 | F10 (0.49) | F10F2LMNAMAPK1NLRP1 | |
| Hydrochloric Acid SCHEMBL5901060 | 0.86 | F10 (0.49) | F10F2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8266229 | 0.85 | F10 (0.52) | F10F2LMNAMAPK1NLRP1 | |
| Hydrochloric Acid SCHEMBL5177126 | 0.84 | F10 (0.51) | F10F2EPHX2PLAUDDR1 | |
| Hydrochloric Acid SCHEMBL5900704 | 0.83 | F10 (0.49) | F10F2NPC1RAB9ADDR1 | |
| SCHEMBL8266378 | 0.83 | F10 (0.48) | F10F2LMNAEPHX2NPC1 | |
| Hydrochloric Acid SCHEMBL5900675 | 0.82 | F10 (0.47) | F10F2LMNAEPHX2NPC1 | |
| SCHEMBL8266411 | 0.82 | F10 (0.51) | F10F2GAAEPHX2NPC1 | |
| Hydrochloric Acid SCHEMBL5086255 | 0.81 | F10 (0.50) | F10F2GAAEPHX2NPC1 | |
| SCHEMBL8264858 | 0.81 | F10 (0.49) | F10F2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006027135-A1 | 4-AMINOMETHYL BENZAMIDINE DERIVATIVES AND THEIR USE AS FACTOR VIIIA INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-03-16 | — | — | WO | disclosed |