Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 9/20 | 0.47 |
| ▸ | PGR | P06401 | 8/20 | 0.39 |
| ▸ | TDP2 | O95551 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7562089 | 0.95 | BACE1 (0.45) | BACE1PGRTDP2 | |
| SCHEMBL7540494 | 0.80 | BACE1 (0.56) | BACE1PGR | |
| SCHEMBL7555327 | 0.77 | BACE1 (0.46) | BACE1PGR | |
| SCHEMBL7537531 | 0.77 | BACE1 (0.56) | BACE1PGR | |
| SCHEMBL2955293 | 0.77 | BACE1 (0.57) | BACE1PGR | |
| SCHEMBL7604353 | 0.75 | BACE1 (0.46) | BACE1PGR | |
| SCHEMBL7539653 | 0.74 | BACE1 (0.54) | BACE1PGR | |
| SCHEMBL7535080 | 0.74 | BACE1 (0.47) | BACE1PGRTDP2 | |
| SCHEMBL7604533 | 0.74 | BACE1 (0.47) | BACE1PGR | |
| SCHEMBL7600666 | 0.74 | BACE1 (0.47) | BACE1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006065277-A2 | HETEROCYCLIC ASPARTYL PROTEASE INHIBITORS | SCHERING CORPORATION (US) | 2006-06-22 | — | — | WO | disclosed |