Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK1D | Q8IU85 | 8/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 9/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 9/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8267651 | 0.93 | CHRM2 (0.37) | CAMK1DHTR2CHCRTR1HCRTR2TACR1 | |
| SCHEMBL11923185 | 0.90 | HCRTR2 (0.36) | CAMK1DHTR2CHCRTR1HCRTR2 | |
| SCHEMBL11923197 | 0.90 | GPBAR1 (0.36) | CAMK1DHTR2CHCRTR1HCRTR2TACR1 | |
| SCHEMBL11923211 | 0.87 | TACR1 (0.39) | CAMK1DHTR2CTACR1 | |
| SCHEMBL11923170 | 0.87 | CCNE1 (0.38) | CAMK1DHCRTR1HCRTR2 | |
| SCHEMBL11923264 | 0.87 | MAPT (0.35) | CAMK1DHCRTR1HCRTR2TACR1 | |
| SCHEMBL11923227 | 0.81 | HSD17B10 (0.43) | CAMK1DHCRTR1HCRTR2TACR1 | |
| SCHEMBL8266031 | 0.80 | HCRTR2 (0.36) | CAMK1DHCRTR1HCRTR2TACR1 | |
| SCHEMBL8266820 | 0.80 | HCRTR2 (0.36) | CAMK1DHCRTR1HCRTR2TACR1 | |
| SCHEMBL11923210 | 0.80 | HCRTR2 (0.36) | CAMK1DHCRTR1HCRTR2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006050476-A2 | PYRIMIDINE DERIVATIVES AS ION CHANNEL MODULATORS AND METHODS OF USE | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2006-05-11 | — | — | WO | disclosed |