Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 7/20 | 0.39 |
| ▸ | F10 | P00742 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | F3 | P13726 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5086284 | 0.99 | CA1 (0.41) | CA1CA2POLBF2F7 | |
| SCHEMBL5564415 | 0.89 | CA1 (0.44) | CA1CA2POLBF2F7 | |
| SCHEMBL5178502 | 0.87 | CA1 (0.41) | CA1CA2POLBF2F7 | |
| SCHEMBL8266398 | 0.87 | F2 (0.44) | CA1CA2POLBF2F7 | |
| Hydrochloric Acid SCHEMBL5178497 | 0.86 | CA1 (0.41) | CA1CA2POLBF2F7 | |
| Hydrochloric Acid SCHEMBL5089175 | 0.86 | F2 (0.43) | CA1CA2POLBF2F7 | |
| Hydrochloric Acid SCHEMBL5089572 | 0.84 | CA1 (0.43) | CA1CA2POLBF2F7 | |
| SCHEMBL8267082 | 0.84 | HDAC8 (0.53) | CA1CA2F2KLKB1F10 | |
| Hydrochloric Acid SCHEMBL5094118 | 0.83 | HDAC8 (0.52) | CA1CA2F2KLKB1F10 | |
| Hydrochloric Acid SCHEMBL5900692 | 0.83 | F2 (0.47) | POLBF2F7KLKB1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006027135-A1 | 4-AMINOMETHYL BENZAMIDINE DERIVATIVES AND THEIR USE AS FACTOR VIIIA INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-03-16 | — | — | WO | disclosed |