Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GCK | P35557 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.34 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 5/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4471595 | 0.90 | PDE4A (0.44) | SMN1; SMN2PDE4AHPGDPDE4DPDE4B | |
| SCHEMBL5307360 | 0.81 | GAA (0.45) | SMN1; SMN2TP53TSHRPDE4AHPGD | |
| SCHEMBL13405862 | 0.81 | PDE4A (0.45) | SMN1; SMN2PDE4AHPGDPDE4DPDE4B | |
| SCHEMBL13605240 | 0.80 | SMN1; SMN2 (0.40) | SMN1; SMN2ADORA1TMIGD3TP53TSHR | |
| SCHEMBL4471223 | 0.80 | PDE4A (0.42) | SMN1; SMN2PDE4AHPGDPDE4DPDE4B | |
| SCHEMBL4473617 | 0.80 | SMN1; SMN2 (0.39) | SMN1; SMN2ADORA1TMIGD3TP53TSHR | |
| SCHEMBL27702539 | 0.80 | SMN1; SMN2 (0.39) | SMN1; SMN2ADORA1TMIGD3TP53TSHR | |
| SCHEMBL4473807 | 0.80 | GAA (0.46) | SMN1; SMN2TP53TSHRPDE4AHPGD | |
| SCHEMBL4476073 | 0.79 | HPGD (0.46) | SMN1; SMN2TP53PDE4AHPGDPDE4D | |
| SCHEMBL4462219 | 0.79 | SMN1; SMN2 (0.38) | SMN1; SMN2ADORA1TMIGD3TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006044955-A1 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2006-04-27 | — | — | WO | disclosed |