Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 6/20 | 0.67 |
| ▸ | F2 | P00734 | 3/20 | 0.44 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.38 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5900590 | 0.99 | F10 (0.66) | F10F2DDR1HTTKMT2A | |
| SCHEMBL5094724 | 0.94 | F10 (0.66) | F10F2DDR1HTTKMT2A | |
| SCHEMBL8265923 | 0.93 | F10 (0.63) | F10F2DDR1HTTKMT2A | |
| Hydrochloric Acid SCHEMBL5089599 | 0.93 | F10 (0.63) | F10F2DDR1HTTKMT2A | |
| SCHEMBL5088302 | 0.93 | F10 (0.63) | F10F2DDR1HTTKMT2A | |
| Hydrochloric Acid SCHEMBL5901004 | 0.93 | F10 (0.63) | F10F2DDR1HTTKMT2A | |
| Hydrochloric Acid SCHEMBL5088297 | 0.92 | F10 (0.62) | F10F2DDR1HTTKMT2A | |
| SCHEMBL8264960 | 0.92 | F10 (0.62) | F10F2DDR1HTTKMT2A | |
| Hydrochloric Acid SCHEMBL5088320 | 0.92 | F10 (0.62) | F10F2DDR1HTTKMT2A | |
| SCHEMBL8265313 | 0.92 | F10 (0.62) | F10F2DDR1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006027135-A1 | 4-AMINOMETHYL BENZAMIDINE DERIVATIVES AND THEIR USE AS FACTOR VIIIA INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-03-16 | — | — | WO | disclosed |