Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.57 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | F2 | P00734 | 2/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27546340 | 1.00 | PRMT5 (0.57) | PRMT5WDR77KMT2AGAAHTT | |
| SCHEMBL25725225 | 0.89 | PRMT5 (0.60) | PRMT5WDR77KMT2AGAAHTT | |
| SCHEMBL14075589 | 0.86 | PRMT5 (0.57) | PRMT5WDR77KMT2AGAAHTT | |
| SCHEMBL27583915 | 0.85 | PRMT5 (0.56) | PRMT5WDR77KMT2AGAAHTT | |
| SCHEMBL5944260 | 0.84 | PRMT5 (0.55) | PRMT5WDR77KMT2AGAAHTT | |
| SCHEMBL6690453 | 0.84 | PRMT5 (0.55) | PRMT5WDR77KMT2AGAAHTT | |
| SCHEMBL5944400 | 0.84 | PRMT5 (0.55) | PRMT5WDR77KMT2AGAAHTT | |
| SCHEMBL1051160 | 0.83 | PRMT5 (0.60) | PRMT5WDR77KMT2AGAAHTT | |
| SCHEMBL13969656 | 0.81 | PRMT5 (0.64) | PRMT5WDR77KMT2AGAAHTT | |
| SCHEMBL6114507 | 0.81 | PRMT5 (0.68) | PRMT5WDR77KMT2AGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006060122-A9 | CARDIOTONIC COMPOUNDS WITH INHIBITORY ACTIVITY AGAINST BETA-ADRENERGIC RECEPTORS AND PHOSPHODIESTERASE | ARTESIAN THERAPEUTICS INC (US) | 2006-08-17 | — | — | WO | disclosed |