Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13373282 | 0.85 | — | — | |
| SCHEMBL7566987 | 0.82 | TSHR (0.41) | TSHR | |
| SCHEMBL12062579 | 0.82 | TSHR (0.41) | TSHR | |
| SCHEMBL7561678 | 0.74 | TSHR (0.35) | TSHR | |
| SCHEMBL13930290 | 0.73 | — | — | |
| SCHEMBL18773846 | 0.72 | — | — | |
| SCHEMBL8827724 | 0.72 | TSHR (0.33) | TSHR | |
| SCHEMBL16907174 | 0.72 | TSHR (0.33) | TSHR | |
| SCHEMBL7360672 | 0.72 | TSHR (0.33) | TSHR | |
| SCHEMBL14984227 | 0.72 | TSHR (0.33) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006060127-A2 | COMPOUNDS WITH MIXED PDE-INHIBITORY AND β-ADRENERGIC ANTAGONIST OR PARTIAL AGONIST ACTIVITY FOR TREATMENT OF HEART FAILURE | ARTESIAN THERAPEUTICS, INC. (US) | 2006-06-08 | — | — | WO | disclosed |