Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 7/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2202270 | 1.00 | MCHR1 (0.72) | MCHR1MEN1KMT2AMAPTHPGD | |
| SCHEMBL2202275 | 1.00 | MCHR1 (0.72) | MCHR1MEN1KMT2AMAPTHPGD | |
| SCHEMBL2199621 | 0.90 | MCHR1 (0.69) | MCHR1MEN1KMT2AMAPTHPGD | |
| SCHEMBL12510833 | 0.90 | MCHR1 (0.69) | MCHR1MEN1KMT2AMAPTHPGD | |
| SCHEMBL2199619 | 0.90 | MCHR1 (0.69) | MCHR1MEN1KMT2AMAPTHPGD | |
| SCHEMBL12510797 | 0.88 | MCHR1 (0.69) | MCHR1MEN1KMT2AMAPTHPGD | |
| SCHEMBL4160298 | 0.88 | MCHR1 (0.69) | MCHR1MEN1KMT2AMAPTHPGD | |
| SCHEMBL4147326 | 0.88 | MCHR1 (0.77) | MCHR1MEN1KMT2AMAPTHPGD | |
| SCHEMBL2200131 | 0.88 | MCHR1 (0.77) | MCHR1MEN1KMT2AMAPTHPGD | |
| SCHEMBL2200126 | 0.88 | MCHR1 (0.77) | MCHR1MEN1KMT2AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977489-B2 | Benzylthiazolone inhibitors of estrogen-related receptors (ERR) | EXELIXIS, INC. (US) | 2011-07-12 | — | — | US | disclosed |
| WO-2006047269-A2 | PHARMACEUTICAL COMPOSITIONS | EXELIXIS, INC. (US) | 2006-05-04 | — | — | WO | disclosed |