Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ1 | P51787 | 6/20 | 0.52 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.48 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL630185 | 1.00 | KCNQ1 (0.52) | KCNQ1HCRTR1HCRTR2POLBLMNA | |
| SCHEMBL1382694 | 1.00 | KCNQ1 (0.52) | KCNQ1HCRTR1HCRTR2POLBLMNA | |
| SCHEMBL630034 | 0.91 | KCNQ1 (0.56) | KCNQ1HCRTR1HCRTR2POLBMMP1 | |
| SCHEMBL1380661 | 0.91 | KCNQ1 (0.56) | KCNQ1HCRTR1HCRTR2POLBMMP1 | |
| SCHEMBL630021 | 0.90 | KCNQ1 (0.44) | KCNQ1HCRTR1HCRTR2POLBLMNA | |
| SCHEMBL1383354 | 0.85 | KCNQ1 (0.48) | KCNQ1HCRTR1HCRTR2POLBBDKRB1 | |
| SCHEMBL630109 | 0.85 | MEN1 (0.48) | KCNQ1HCRTR1HCRTR2POLBBDKRB1 | |
| SCHEMBL629996 | 0.85 | KCNQ1 (0.48) | KCNQ1HCRTR1HCRTR2POLBBDKRB1 | |
| SCHEMBL630207 | 0.83 | KCNQ1 (0.54) | KCNQ1HCRTR1HCRTR2LMNATSHR | |
| SCHEMBL1382042 | 0.83 | KCNQ1 (0.54) | KCNQ1HCRTR1HCRTR2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006012256-A2 | FKBP BINDING COMPOSITION AND PHARMACEUTICAL USE THEREOF | AVENTIS PHARMACEUTICALS INC. (US) | 2006-02-02 | — | — | WO | disclosed |