Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 20/20 | 1.00 |
| ▸ | MC3R | P41968 | 8/20 | 1.00 |
| ▸ | MC5R | P33032 | 7/20 | 0.93 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4957300 | 1.00 | MC4R (1.00) | MC4RMC3RMC5R | |
| SCHEMBL14204839 | 1.00 | MC4R (1.00) | MC4RMC3RMC5R | |
| SCHEMBL14294628 | 0.91 | MC4R (0.83) | MC4RMC3RMC5R | |
| SCHEMBL14270807 | 0.91 | MC4R (0.83) | MC4RMC3RMC5R | |
| SCHEMBL14270802 | 0.91 | MC4R (0.83) | MC4RMC3RMC5R | |
| SCHEMBL14294627 | 0.91 | MC4R (0.83) | MC4RMC3RMC5R | |
| SCHEMBL14294630 | 0.91 | MC4R (0.83) | MC4RMC3RMC5R | |
| SCHEMBL14270842 | 0.91 | MC4R (0.83) | MC4RMC3RMC5R | |
| SCHEMBL14270810 | 0.91 | MC4R (0.83) | MC4RMC3RMC5R | |
| SCHEMBL14270805 | 0.91 | MC4R (0.83) | MC4RMC3RMC5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006036770-A2 | COMBINATION THERAPY FOR THE TREATMENT OF OBESITY | MERCK & CO., INC. (US) | 2006-04-06 | — | — | WO | disclosed |