Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8268942 | 0.86 | FFAR1 (0.41) | ALDH1A1KDM4ESMN1; SMN2FFAR1MEN1 | |
| SCHEMBL8268223 | 0.82 | FFAR4 (0.37) | — | |
| SCHEMBL8268220 | 0.81 | PPARD (0.36) | — | |
| SCHEMBL8268224 | 0.74 | FFAR1 (0.33) | FFAR1 | |
| SCHEMBL8269004 | 0.72 | FFAR1 (0.32) | FFAR1DRD2 | |
| SCHEMBL8268701 | 0.71 | FFAR1 (0.39) | FFAR1 | |
| SCHEMBL8268210 | 0.70 | — | — | |
| SCHEMBL8269966 | 0.69 | FFAR1 (0.39) | FFAR1 | |
| SCHEMBL8267673 | 0.69 | KDM4E (0.45) | ALDH1A1KDM4ESMN1; SMN2FFAR1MEN1 | |
| SCHEMBL8268263 | 0.69 | FFAR1 (0.40) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006043064-A1 | PIPERIDINES AND RELATED COMPOUNDS FOR TREATMENT OF ALZHEIMER'S DISEASE | MERCK SHARP & DOHME LIMITED (GB) | 2006-04-27 | — | — | WO | disclosed |