Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.68 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.59 |
| ▸ | POU2F2 | P09086 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | POU2F1 | P14859 | 1/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.56 |
| ▸ | HRH2 | P25021 | 1/20 | 0.56 |
| ▸ | MC4R | P32245 | 1/20 | 0.56 |
| ▸ | FAP | Q12884 | 1/20 | 0.56 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.56 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.56 |
| ▸ | GHSR | Q92847 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13923851 | 0.92 | DPP4 (0.67) | DPP4CHRM1 | |
| SCHEMBL8271374 | 0.89 | DPP4 (0.63) | DPP4CHRM1POU2F2ADORA3POU2F1 | |
| SCHEMBL8269946 | 0.89 | DPP4 (0.61) | DPP4CHRM1 | |
| SCHEMBL13923876 | 0.88 | DPP4 (0.68) | DPP4CHRM1POU2F2ADORA3POU2F1 | |
| SCHEMBL8269359 | 0.87 | DPP4 (0.61) | DPP4CHRM1POU2F2ADORA3POU2F1 | |
| SCHEMBL8269369 | 0.87 | DPP4 (0.79) | DPP4CHRM1 | |
| SCHEMBL13923888 | 0.87 | DPP4 (0.63) | DPP4CHRM1POU2F2ADORA3POU2F1 | |
| SCHEMBL3952628 | 0.86 | DPP4 (0.78) | DPP4 | |
| SCHEMBL8268760 | 0.86 | DPP4 (0.62) | DPP4CHRM1 | |
| SCHEMBL13923850 | 0.86 | DPP4 (0.67) | DPP4CHRM1POU2F2ADORA3POU2F1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006027204-A1 | 8-(3-AMINO-PIPERIDIN-1-YL)-7-(BUT-2-INYL)-XANTHINES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-03-16 | — | — | WO | disclosed |