Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 19/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL87858 | 0.79 | GSK3B (0.51) | GSK3BCYP2D6CYP1A2CYP3A4 | |
| SCHEMBL8268075 | 0.74 | GSK3B (0.63) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL2116043 | 0.74 | GSK3B (0.64) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL87832 | 0.74 | GSK3B (0.62) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL88129 | 0.73 | GSK3B (0.55) | GSK3BCYP2D6CYP1A2CYP3A4 | |
| SCHEMBL88127 | 0.73 | GSK3B (0.51) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL87782 | 0.73 | GSK3B (0.54) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL81961 | 0.73 | GSK3B (0.69) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL87939 | 0.73 | GSK3B (0.72) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL695999 | 0.71 | GSK3B (0.74) | GSK3BCYP2D6CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006036015-A2 | 6- (PYRIDINYL) -4-PYRIMIDONE DERIVATES AS TAU PROTEIN KINASE 1 INHIBITORS | MITSUBISHI PHARMA CORPORATION (JP) | 2006-04-06 | — | — | WO | disclosed |