Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.73 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.73 |
| ▸ | FAP | Q12884 | 3/20 | 0.73 |
| ▸ | POU2F2 | P09086 | 1/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.73 |
| ▸ | POU2F1 | P14859 | 1/20 | 0.73 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.73 |
| ▸ | HRH2 | P25021 | 1/20 | 0.73 |
| ▸ | MC4R | P32245 | 1/20 | 0.73 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.73 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.73 |
| ▸ | GHSR | Q92847 | 1/20 | 0.73 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13923911 | 0.96 | DPP4 (0.75) | DPP4CHRM1FAPPOU2F2ADORA3 | |
| SCHEMBL3947346 | 0.94 | DPP4 (0.78) | DPP4CHRM1FAPPOU2F2ADORA3 | |
| SCHEMBL3947350 | 0.94 | DPP4 (0.78) | DPP4CHRM1FAPPOU2F2ADORA3 | |
| SCHEMBL8270401 | 0.93 | DPP4 (0.74) | DPP4CHRM1FAPPOU2F2ADORA3 | |
| SCHEMBL13945573 | 0.92 | DPP4 (0.60) | DPP4CHRM1FAPPOU2F2ADORA3 | |
| SCHEMBL3953019 | 0.91 | DPP4 (0.79) | DPP4CHRM1FAPPOU2F2ADORA3 | |
| SCHEMBL3953023 | 0.91 | DPP4 (0.79) | DPP4CHRM1FAPPOU2F2ADORA3 | |
| SCHEMBL8270394 | 0.91 | DPP4 (0.74) | DPP4CHRM1FAPPOU2F2ADORA3 | |
| SCHEMBL13923910 | 0.90 | DPP4 (0.73) | DPP4CHRM1FAPPOU2F2ADORA3 | |
| SCHEMBL1773133 | 0.90 | DPP4 (0.83) | DPP4CHRM1FAPPOU2F2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7495003-B2 | 8-(3-amino-piperidin-1-yl)-7-(but-2-ynyl)-xanthines, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-02-24 | — | — | US | disclosed |
| WO-2006027204-A1 | 8-(3-AMINO-PIPERIDIN-1-YL)-7-(BUT-2-INYL)-XANTHINES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-03-16 | — | — | WO | disclosed |