Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 4/20 | 0.37 |
| ▸ | ERN1 | O75460 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 2/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8271898 | 0.83 | TNKS (0.38) | GRM2CNR2FGFR1PIK3CG | |
| SCHEMBL2026656 | 0.81 | CHRM1 (0.47) | GRM2CHRM1CNR2ERN1CYP11B2 | |
| SCHEMBL2024043 | 0.73 | TNKS (0.41) | GRM2CHRM1FGFR1PIK3CG | |
| SCHEMBL2026458 | 0.71 | TNKS (0.43) | CNR2PIK3CG | |
| SCHEMBL2023271 | 0.67 | GRM2 (0.54) | GRM2FGFR1PIK3CG | |
| SCHEMBL2026378 | 0.64 | ALK (0.44) | GRM2CHRM1CNR2FGFR1PIK3CG | |
| SCHEMBL2021690 | 0.64 | GRM2 (0.58) | GRM2PIK3CG | |
| SCHEMBL2027009 | 0.63 | PIK3CG (0.55) | PIK3CGCYP3A4 | |
| SCHEMBL12443074 | 0.63 | PIK3CG (0.55) | PIK3CGCYP3A4 | |
| SCHEMBL2024082 | 0.61 | TNKS (0.43) | GRM2CNR2FGFR1PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006020879-A1 | ISOINDOLONE COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR POTENTIATORS | ASTRAZENECA AB (SE) | 2006-02-23 | — | — | WO | disclosed |