Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 20/20 | 0.57 |
| ▸ | PDE11A | Q9HCR9 | 14/20 | 0.57 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13918971 | 0.92 | PDE4B (0.67) | PDE4BPDE11APDE10A | |
| SCHEMBL13918964 | 0.92 | PDE4B (0.67) | PDE4BPDE11APDE10A | |
| SCHEMBL13919295 | 0.83 | PDE4B (0.67) | PDE4BPDE11APDE10A | |
| SCHEMBL13918981 | 0.82 | PDE4B (0.78) | PDE4BPDE11APDE10A | |
| SCHEMBL8272919 | 0.82 | PDE4B (0.78) | PDE4BPDE11APDE10A | |
| SCHEMBL8272909 | 0.81 | PDE4B (0.54) | PDE4BPDE11APDE10A | |
| SCHEMBL13919348 | 0.81 | PDE4B (0.63) | PDE4BPDE11APDE10A | |
| SCHEMBL13919253 | 0.80 | PDE4B (0.61) | PDE4BPDE11APDE10A | |
| SCHEMBL12162700 | 0.79 | PDE4B (0.49) | PDE4BPDE11APDE10A | |
| SCHEMBL8276370 | 0.79 | PDE4B (0.59) | PDE4BPDE11APDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005116009-A1 | SUBSTITUTED 2-QUINOLYL-OXAZOLES USEFUL AS PDE4 INHIBITORS | SCHERING CORPORATION (US) | 2005-12-08 | — | — | WO | disclosed |