Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR3 | O60755 | 20/20 | 1.00 |
| ▸ | HTR4 | Q13639 | 1/20 | 1.00 |
| ▸ | DRD5 | P21918 | 2/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL916991 | 1.00 | GALR3 (1.00) | GALR3HTR4DRD5ADRA1A | |
| SCHEMBL916990 | 1.00 | GALR3 (1.00) | GALR3HTR4DRD5ADRA1A | |
| SCHEMBL918247 | 0.93 | GALR3 (0.87) | GALR3HTR4DRD5ADRA1A | |
| SCHEMBL3240615 | 0.93 | GALR3 (0.87) | GALR3HTR4DRD5ADRA1A | |
| SCHEMBL915968 | 0.91 | GALR3 (0.83) | GALR3HTR4DRD5ADRA1A | |
| SCHEMBL915969 | 0.91 | GALR3 (0.83) | GALR3HTR4DRD5ADRA1A | |
| SCHEMBL916679 | 0.91 | GALR3 (0.83) | GALR3HTR4DRD5ADRA1A | |
| SCHEMBL916677 | 0.91 | GALR3 (0.83) | GALR3HTR4DRD5ADRA1A | |
| SCHEMBL8164607 | 0.91 | GALR3 (0.83) | GALR3HTR4DRD5ADRA1A | |
| SCHEMBL6904884 | 0.91 | GALR3 (0.83) | GALR3HTR4DRD5ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050192337-A1 | Processes and polymorphs of diaryl-indolone galr3 antagonists | H. LUNDBECK A/S (DK) | 2005-09-01 | — | — | US | disclosed |
| US-20050192337-A1 | Processes and polymorphs of diaryl-indolone galr3 antagonists | H. LUNDBECK A/S (DK) | 2005-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050192337-A1 | Processes and polymorphs of diaryl-indolone galr3 antagonists | GALR3, GALR1, GALR2 | GALR3 1/4885HTR4 266/4885DRD5 1739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.