SCHEMBL8274

SCHEMBL8274

C1=Cc2ccccc2SN1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.34
GAA P10253 2/20 0.32
MAPT P10636 2/20 0.32
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
BCHE P06276 1/20 0.31
POLB P06746 1/20 0.31
CYP3A4 P08684 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
ALOX15 P16050 1/20 0.31
ALOX12 P18054 1/20 0.31
MAOA P21397 1/20 0.31
CNR1 P21554 1/20 0.31
ACHE P22303 1/20 0.31
PTGS1 P23219 1/20 0.31
SLC6A2 P23975 1/20 0.31
HTR2C P28335 1/20 0.31
PTGS2 P35354 1/20 0.31
SNCA P37840 1/20 0.31
SLC6A3 Q01959 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5686105 1.00 PARP1 (0.34) PARP1GAAMAPTMEN1CYP1A2
SCHEMBL3187256 0.98 PARP1 (0.33) PARP1GAAMAPTMEN1CYP1A2
Hydrochloric Acid SCHEMBL6424271 0.98 PARP1 (0.38) PARP1GAAMAPTMEN1CYP1A2
Ammonia Solution, Strong SCHEMBL10515014 0.98 PARP1 (0.33) PARP1GAAMAPTMEN1CYP1A2
SCHEMBL38654629 0.98 PARP1 (0.33) PARP1GAAMAPTMEN1CYP1A2
Fluoride SCHEMBL28896860 0.96 PARP1 (0.32) PARP1GAAMAPT
Hydrochloric Acid SCHEMBL8939837 0.96 PARP1 (0.36) PARP1GAAMAPT
Formaldehyde SCHEMBL28424513 0.94 PARP1 (0.31) PARP1
SCHEMBL28600218 0.87 PARP1 (0.32) PARP1
Phenothiazine SCHEMBL28347846 0.85 NOX1 (0.59) GAAMAPTMEN1CYP1A2BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4166 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122005810-A Application of peroxide reductase 1 as target in preparation of IS therapeutic drugs 国科宁波生命与健康产业研究院 2026-05-12 CN claimed
EP-4630446-A1 ENGINEERED SWITCHES FOR IMMUNE CELL ACTIVITY AND METHODS OF USE THEREOF Dynamic Cell Therapies, Inc. (US) 2025-10-15 EP claimed
EP-4630043-A1 IMMUNE-ACTIVATING COMPLEXES Dynamic Cell Therapies, Inc. (US) 2025-10-15 EP claimed
CN-116970145-B Amphiphilic triblock polymer, stimulus-responsive nanoparticle and preparation method thereof 中国科学技术大学 2025-06-13 CN claimed
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO claimed
CN-120020131-A Aromatic ring benzothiazine derivative and medical application thereof 杭州百诚医药科技股份有限公司 2025-05-20 CN claimed
CN-119745702-A Zirconia ceramic block for manufacturing false tooth 深圳玉汝成口腔材料有限公司 2025-04-04 CN claimed
CN-119744352-A Intracellular ligation of photocatalysts for photoresponsive, probe-mediated protein labeling 美国锡德治疗有限公司 2025-04-01 CN claimed
CN-119504645-A Method for synthesizing N- (acetamidomethyl) benzothiazine-4-ketone 常州大学 2025-02-25 CN claimed
US-20250057874-A1 SYNTHETIC MELANIN NANOPARTICLES AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-02-20 US claimed
EP-0140886-A4 FILM BADGE FOR DETERMINING CARBONYL COMPOUNDS. LITTLE INC A (US) 1985-09-02 EP claimed
EP-0079639-B1 A NEW ANTI-INFLAMMATORY DRUG SPA SOCIETA' PRODOTTI ANTIBIOTICI S.p.A. (IT) 1985-07-24 EP claimed
EP-0042435-B1 BENZOTHIAZINE DERIVATIVES Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1985-06-12 EP claimed
EP-0140886-A1 FILM BADGE FOR DETERMINING CARBONYL COMPOUNDS. LITTLE INC A (US) 1985-05-15 EP claimed
US-4490292-A 1,5-Benzothiazepine derivatives and production thereof HAMARI CHEMICALS, LTD. (JP) 1984-12-25 US claimed
WO-1984004165-A1 FILM BADGE FOR DETERMINING CARBONYL COMPOUNDS LITTLE INC A (US) 1984-10-25 WO claimed
US-4434163-A Water-soluble benzothiazine dioxide salts PFIZER INC. (US) 1984-02-28 US claimed
US-4434164-A AMINE SALTS OF N-/2-PYRIDYL/-2-METHYL-4-HYDROXY--2H-1,2-BENZOTHIAZINE-3-CARBOXAMIDE,-1,1 -DIOXIDE PFIZER INC. (US) 1984-02-28 US claimed
EP-0042435-A1 BENZOTHIAZINE DERIVATIVES Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1981-12-30 EP claimed
US-4294961-A REMOVAL OF METALS HENKEL CORPORATION (US) 1981-10-13 US claimed