Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | PRKCI | P41743 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15647796 | 0.90 | ATM (0.40) | KDM4EGPR3ALDH1A1CYP1A2MAPK1 | |
| SCHEMBL2513055 | 0.77 | KDM4E (0.37) | KDM4EGPR3ALDH1A1CYP1A2PARP1 | |
| SCHEMBL8274126 | 0.76 | KDM4E (0.39) | KDM4EGPR3ALDH1A1CYP1A2MAPK1 | |
| SCHEMBL2522030 | 0.72 | KDM4E (0.39) | KDM4EGPR3MAPK1 | |
| SCHEMBL1654471 | 0.71 | PARP1 (0.38) | KDM4EALDH1A1CYP1A2MAPTPARP1 | |
| SCHEMBL1655936 | 0.71 | ATM (0.36) | KDM4EALDH1A1CYP1A2MAPTPARP1 | |
| SCHEMBL2522033 | 0.71 | KDM4E (0.38) | KDM4EGPR3MAPK1 | |
| SCHEMBL18576434 | 0.69 | KDM4E (0.47) | KDM4EGPR3ALDH1A1CYP1A2MAPK1 | |
| SCHEMBL6639653 | 0.69 | KDM4E (0.39) | KDM4EGPR3MAPK1 | |
| SCHEMBL8274241 | 0.68 | KMT2A (0.39) | KDM4EALDH1A1CYP1A2MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705146-B2 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-27 | — | — | US | disclosed |
| US-7705146-B2 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-27 | — | — | US | disclosed |
| WO-2006000085-A1 | HEPATITIS C INHIBITOR PEPTIDE ANALOGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-01-05 | — | — | WO | disclosed |