Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 20/20 | 0.47 |
| ▸ | PDE11A | Q9HCR9 | 5/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13920541 | 0.90 | PDE4B (0.54) | PDE4BPDE11APDE10APDE3A | |
| SCHEMBL13920535 | 0.89 | PDE4B (0.49) | PDE4BPDE11APDE10A | |
| SCHEMBL8274207 | 0.80 | PDE4B (0.56) | PDE4BPDE11APDE10A | |
| SCHEMBL8275375 | 0.78 | PDE4B (0.47) | PDE4BPDE11APDE10APDE3A | |
| SCHEMBL8275382 | 0.78 | PDE4B (0.55) | PDE4BPDE11APDE10A | |
| SCHEMBL13920539 | 0.77 | PDE4B (0.62) | PDE4BPDE11APDE10A | |
| SCHEMBL8274209 | 0.76 | PDE4B (0.47) | PDE4BPDE11APDE10A | |
| SCHEMBL8274726 | 0.76 | PDE4B (0.65) | PDE4BPDE11APDE10A | |
| SCHEMBL16350363 | 0.75 | PDE4B (0.49) | PDE4BPDE11APDE10APDE3A | |
| SCHEMBL16350362 | 0.75 | PDE4B (0.44) | PDE4BPDE11APDE10APDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005116009-A1 | SUBSTITUTED 2-QUINOLYL-OXAZOLES USEFUL AS PDE4 INHIBITORS | SCHERING CORPORATION (US) | 2005-12-08 | — | — | WO | disclosed |