Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 20/20 | 0.81 |
| ▸ | PDE11A | Q9HCR9 | 16/20 | 0.81 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8272889 | 0.95 | PDE4B (0.87) | PDE4BPDE11APDE4D | |
| SCHEMBL13920555 | 0.94 | PDE4B (0.91) | PDE4BPDE11APDE4D | |
| SCHEMBL8275298 | 0.90 | PDE4B (1.00) | PDE4BPDE11APDE4D | |
| SCHEMBL8272891 | 0.87 | PDE4B (0.87) | PDE4BPDE11APDE4D | |
| SCHEMBL13918420 | 0.85 | PDE4B (0.78) | PDE4BPDE11APDE4D | |
| SCHEMBL8275063 | 0.85 | PDE4B (0.88) | PDE4BPDE11APDE4D | |
| SCHEMBL13918352 | 0.84 | PDE4B (1.00) | PDE4BPDE11APDE4D | |
| SCHEMBL13918509 | 0.83 | PDE4B (0.87) | PDE4BPDE11APDE4D | |
| SCHEMBL8275090 | 0.83 | PDE4B (1.00) | PDE4BPDE11APDE4D | |
| SCHEMBL8276356 | 0.83 | PDE4B (1.00) | PDE4BPDE11APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005116009-A1 | SUBSTITUTED 2-QUINOLYL-OXAZOLES USEFUL AS PDE4 INHIBITORS | SCHERING CORPORATION (US) | 2005-12-08 | — | — | WO | disclosed |