Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 20/20 | 0.59 |
| ▸ | PDE11A | Q9HCR9 | 14/20 | 0.56 |
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13919115 | 0.94 | PDE4B (0.59) | PDE4BPDE11APDE10A | |
| SCHEMBL8274590 | 0.90 | PDE4B (0.62) | PDE4BPDE11APDE10A | |
| SCHEMBL8274593 | 0.90 | PDE4B (0.58) | PDE4BPDE11APDE10A | |
| SCHEMBL13919325 | 0.87 | PDE4B (0.62) | PDE4BPDE11APDE10A | |
| SCHEMBL8274585 | 0.87 | PDE4B (0.70) | PDE4BPDE11APDE10A | |
| SCHEMBL13919328 | 0.87 | PDE4B (0.64) | PDE4BPDE11APDE10A | |
| SCHEMBL13920040 | 0.86 | PDE4B (0.76) | PDE4BPDE11APDE10A | |
| SCHEMBL13919801 | 0.86 | PDE4B (0.77) | PDE4BPDE11APDE10A | |
| SCHEMBL13919955 | 0.86 | PDE4B (0.77) | PDE4BPDE11APDE10A | |
| SCHEMBL8272917 | 0.86 | PDE4B (0.77) | PDE4BPDE11APDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005116009-A1 | SUBSTITUTED 2-QUINOLYL-OXAZOLES USEFUL AS PDE4 INHIBITORS | SCHERING CORPORATION (US) | 2005-12-08 | — | — | WO | disclosed |