Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 4/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.35 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8218328 | 0.91 | CHRM4 (0.42) | CHRM4ADAM17RPS6KB1CETPKCNH2 | |
| SCHEMBL8215183 | 0.90 | CHRM4 (0.42) | CHRM4ADAM17RPS6KB1CETPKCNH2 | |
| SCHEMBL8215295 | 0.88 | CHRM4 (0.45) | CHRM4ADAM17CETPUSP30MTOR | |
| SCHEMBL8217224 | 0.87 | CHRM4 (0.43) | CHRM4ADAM17RPS6KB1CETPKCNH2 | |
| SCHEMBL8222096 | 0.87 | CHRM4 (0.43) | CHRM4ADAM17RPS6KB1USP30PDPK1 | |
| SCHEMBL8215167 | 0.86 | CHRM4 (0.47) | CHRM4ADAM17USP30PDPK1 | |
| SCHEMBL8222389 | 0.84 | CHRM4 (0.43) | CHRM4ADAM17RPS6KB1USP30CHRNA7 | |
| SCHEMBL8222101 | 0.83 | CHRM4 (0.44) | CHRM4ADAM17RPS6KB1USP30CHRNA7 | |
| SCHEMBL8224033 | 0.83 | CHRM4 (0.44) | CHRM4ADAM17USP30CHRNA7 | |
| SCHEMBL12216760 | 0.82 | CHRM4 (0.48) | CHRM4ADAM17CETPUSP30MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005121130-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION (US) | 2005-12-22 | — | — | WO | disclosed |