⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3949428 | 0.96 | — | — | |
| SCHEMBL9201379 | 0.74 | — | — | |
| SCHEMBL31376068 | 0.73 | — | — | |
| SCHEMBL1925361 | 0.69 | — | — | |
| SCHEMBL329130 | 0.64 | — | — | |
| SCHEMBL8526388 | 0.61 | — | — | |
| Water SCHEMBL31012143 | 0.61 | — | — | |
| SCHEMBL13156410 | 0.61 | — | — | |
| SCHEMBL29205011 | 0.61 | — | — | |
| SCHEMBL26326511 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3330255-B1 | PROCESS FOR MAKING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMA (US) | 2020-12-09 | — | — | EP | claimed |
| EP-2828272-B1 | CARBENE TRANSFER REAGENT | UNIV JACOBS BREMEN GMBH (DE) | 2016-10-19 | — | — | EP | claimed |
| EP-1924577-B1 | SUBSTITUTED BENZIMIDAZOLES AND METHODS OF PREPARATION | NOVARTIS AG (CH) | 2011-03-30 | — | — | EP | claimed |
| US-20100087444-A1 | IMATINIB MESYLATE | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-04-08 | — | — | US | claimed |
| EP-2120877-A2 | IMATINIB MESYLATE | Dr. Reddy's Laboratories Ltd. (IN) | 2009-11-25 | — | — | EP | claimed |
| WO-2008112722-A2 | IMATINIB MESYLATE | DR. REDDY'S LABORATORIES LTD. (IN) | 2008-09-18 | — | — | WO | claimed |
| EP-0895991-A2 | Halogenating agent | Mitsui Chemicals, Inc. (JP) | 1999-02-10 | — | — | EP | claimed |
| CN-118063349-A | Cyclopropionamide substituted benzamide derivative and preparation method and application thereof | 山东省联合农药工业有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-118044519-A | Molecules having pesticidal utility, and intermediates, compositions and methods related thereto | 科迪华农业科技有限责任公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-117580586-A | Fc glycan remodelling for site-specific antibody conjugation and uses thereof | 马里兰大学帕克分校 | 2024-02-20 | — | — | CN | disclosed |
| CN-110072842-B | Molecules having pesticidal utility, and intermediates, compositions and methods related thereto | 科迪华农业科技有限责任公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-117343124-A | Visible light mediated cysteine-based polypeptides and protein chemical modification methods | 上海交通大学 | 2024-01-05 | — | — | CN | disclosed |
| CN-113024481-B | Preparation method of tartaric acid-derived chiral oxazolidine-2-thioketone | 中南民族大学 | 2022-07-15 | — | — | CN | disclosed |
| EP-1531846-A4 | CONJUGATES OF LIGAND, LINKER AND CYTOTOXIC AGENT AND RELATED COMPOSITIONS AND METHODS OF USE | US GOV HEALTH & HUMAN SERV (US) | 2006-04-19 | — | — | EP | disclosed |
| US-20050171014-A1 | Conjugates of ligand linker and cytotoxic agent and related composition and methods of use | GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH (US) | 2005-08-04 | — | — | US | disclosed |
| EP-1531846-A2 | CONJUGATES OF LIGAND, LINKER AND CYTOTOXIC AGENT AND RELATED COMPOSITIONS AND METHODS OF USE | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2005-05-25 | — | — | EP | disclosed |
| CN-1557809-A | Process for synthesis of chiral oxazolidine-2-thioketone compounds | 中国科学院上海有机化学研究所 | 2004-12-29 | — | — | CN | disclosed |
| US-20030187023-A1 | Sulfone derivatives, process for their production and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-10-02 | — | — | US | disclosed |
| WO-2003072754-A2 | CONJUGATES OF LIGAND, LINKER AND CYTOTOXIC AGENT AND RELATED COMPOSITIONS AND METHODS OF USE | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2003-09-04 | — | — | WO | disclosed |
| EP-1302462-A1 | SULFONE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2003-04-16 | — | — | EP | disclosed |