Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8279584 | 0.92 | POLB (0.44) | POLBLMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8280528 | 0.81 | POLB (0.42) | POLBLMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1097027 | 0.79 | MAPK1 (0.47) | POLBLMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL3981673 | 0.75 | POLB (0.41) | POLBLMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL3981676 | 0.72 | HDAC4 (0.41) | POLBLMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1095504 | 0.72 | HDAC4 (0.38) | POLBLMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1095301 | 0.72 | POLB (0.46) | POLBLMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1096298 | 0.71 | POLB (0.45) | POLBLMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1096700 | 0.70 | POLB (0.47) | POLBLMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL3986984 | 0.68 | HDAC4 (0.42) | POLBLMNASMN1; SMN2CYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006002099-A2 | FACTOR XA INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2006-01-05 | — | — | WO | disclosed |