⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1862567 | 0.81 | TSHR (0.44) | — | |
| SCHEMBL10766039 | 0.81 | — | — | |
| SCHEMBL10628467 | 0.80 | TSHR (0.46) | — | |
| SCHEMBL9821419 | 0.80 | — | — | |
| SCHEMBL11273036 | 0.78 | — | — | |
| SCHEMBL148792 | 0.76 | — | — | |
| SCHEMBL14777661 | 0.76 | — | — | |
| SCHEMBL11519589 | 0.76 | — | — | |
| SCHEMBL23732 | 0.76 | — | — | |
| SCHEMBL8852489 | 0.76 | TSHR (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11807664-B2 | Method for producing cyclic organic compound | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-07 | — | — | US | disclosed |
| US-20210147475-A1 | METHOD FOR PRODUCING CYCLIC ORGANIC COMPOUND | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2021-05-20 | — | — | US | disclosed |
| EP-3623378-A1 | METHOD FOR PRODUCING CYCLIC ORGANIC COMPOUND | Chugai Seiyaku Kabushiki Kaisha (JP) | 2020-03-18 | — | — | EP | disclosed |
| US-9765058-B2 | Substituted benzylpyrazoles | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-09-19 | — | — | US | disclosed |
| US-9556187-B2 | Substituted pyrrolo[3′,2′:5,6]pyrido[4,3-d]pyrimidines and JAK inhibitors comprising the same | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-01-31 | — | — | US | disclosed |
| EP-3112370-A1 | TRICYCLIC HETEROCYCLIC COMPOUNDS AND JAK INHIBITORS | Nissan Chemical Industries, Ltd. (JP) | 2017-01-04 | — | — | EP | disclosed |
| US-9403798-B2 | Triazinone compound and T-type calcium channel inhibitor | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2016-08-02 | — | — | US | disclosed |
| US-20160168130-A1 | HETEROARYL SUBSTITUTED PYRAZOLES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-06-16 | — | — | US | disclosed |
| US-20160151370-A1 | Substituted Benzylpyrazoles | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-06-02 | — | — | US | disclosed |
| US-20160145239-A1 | DIAMINOHETEROARYL SUBSTITUTED PYRAZOLES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-05-26 | — | — | US | disclosed |
| US-20100168430-A1 | MULTIKINASE INHIBITOR | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2010-07-01 | — | — | US | disclosed |
| US-20090247524-A1 | HSP90 Inhibitor | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-10-01 | — | — | US | disclosed |
| US-20090030195-A1 | 1-(2H)-ISOQUINOLONE DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-01-29 | — | — | US | disclosed |
| EP-1854792-A1 | 1-(2H)-ISOQUINOLONE DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2007-11-14 | — | — | EP | disclosed |
| US-20070185160-A1 | 1-(2H)-isoquinolone derivative | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2007-08-09 | — | — | US | disclosed |
| EP-1724262-A1 | 1-(2H)-ISOQUINOLONE DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2006-11-22 | — | — | EP | disclosed |
| US-20060217434-A1 | Remedy for viral disease | CHUGAI SEIYAKU KABUSHIKI KAISHA | 2006-09-28 | — | — | US | disclosed |
| EP-0940405-B1 | Organosilicon compounds containing alkenyl groups | WACKER CHEMIE GMBH (DE) | 2002-03-13 | — | — | EP | disclosed |
| US-6252101-B1 | ADDITION-CONDENSATION POLYMER | WACKER-CHEMIE GMBH (DE) | 2001-06-26 | — | — | US | disclosed |
| EP-0430194-A2 | Aryl-alkyl-azoles substituted with many times unsaturated groups, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-06-05 | — | — | EP | disclosed |