Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8293668 | 0.92 | ADRB3 (0.39) | ADRB3ADRA2BADRA2CFAPCYP3A4 | |
| SCHEMBL8295378 | 0.90 | ADRB3 (0.37) | ADRB3ADRA2BADRA2CNAMPTCYP3A4 | |
| SCHEMBL3972597 | 0.90 | ADRB3 (0.37) | ADRB3ADRA2BADRA2CNAMPTCYP3A4 | |
| SCHEMBL8295368 | 0.89 | ADRB3 (0.39) | ADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL8278232 | 0.84 | ADRB3 (0.40) | ADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL13711266 | 0.83 | ADRB3 (0.36) | ADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL11983912 | 0.83 | ADRB3 (0.39) | ADRB3ADRA2BADRA2CNAMPTCYP3A4 | |
| SCHEMBL3974639 | 0.83 | ADRB3 (0.43) | ADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL3969153 | 0.83 | ADRB3 (0.45) | ADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL3969150 | 0.83 | ADRB3 (0.45) | ADRB3ADRA2BADRA2CCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005095403-A2 | MACROCYCLIC COMPOUNDS AS INHIBITORS OF VIRAL REPLICATION | INTERMUNE, INC. (US) | 2005-10-13 | — | — | WO | disclosed |