Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP9 | Q86TI2 | 12/20 | 1.00 |
| ▸ | DPP4 | P27487 | 11/20 | 1.00 |
| ▸ | DPP8 | Q6V1X1 | 10/20 | 1.00 |
| ▸ | DPP7 | Q9UHL4 | 9/20 | 0.53 |
| ▸ | FAP | Q12884 | 1/20 | 0.53 |
| ▸ | GABRP | O00591 | 2/20 | 0.47 |
| ▸ | GABRD | O14764 | 2/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.47 |
| ▸ | GABRE | P78334 | 2/20 | 0.47 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.47 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.47 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10310176 | 1.00 | DPP9 (1.00) | DPP9DPP4DPP8DPP7FAP | |
| SCHEMBL13914365 | 0.88 | DPP9 (0.79) | DPP9DPP4DPP8DPP7FAP | |
| SCHEMBL10280921 | 0.82 | DPP4 (0.69) | DPP9DPP4DPP8GABRPGABRD | |
| SCHEMBL8279681 | 0.80 | DPP9 (0.67) | DPP9DPP4DPP8DPP7GABRP | |
| SCHEMBL15434855 | 0.80 | DPP9 (0.67) | DPP9DPP4DPP8DPP7GABRP | |
| SCHEMBL751142 | 0.79 | DPP4 (0.65) | DPP9DPP4DPP8GABRPGABRD | |
| SCHEMBL29415456 | 0.79 | DPP4 (0.65) | DPP9DPP4DPP8GABRPGABRD | |
| SCHEMBL27996817 | 0.79 | DPP4 (0.65) | DPP9DPP4DPP8GABRPGABRD | |
| SCHEMBL751143 | 0.79 | DPP4 (0.65) | DPP9DPP4DPP8GABRPGABRD | |
| SCHEMBL10162444 | 0.77 | DPP4 (0.63) | DPP9DPP4DPP8GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110218142-A1 | Inhibitors of Dipeptidylpeptidase IV | TRUSTEES OF TUFTS COLLEGE (US) | 2011-09-08 | — | — | US | disclosed |
| US-20090062235-A1 | Inhibitors of Dipeptidylpeptidase IV | TRUSTEES OF TUFTS COLLEGE (US) | 2009-03-05 | — | — | US | disclosed |
| WO-2005082348-A2 | INHIBITORS OF DIPEPTIDYLPEPTIDASE IV FOR REGULATING GLUCOSE METABOLISM | TRUSTEES OF TUFTS COLLEGE (US) | 2005-09-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062235-A1 | Inhibitors of Dipeptidylpeptidase IV | DPP4, DPP3, DPP7 | DPP9 8/4885DPP4 1/4885DPP8 9/4885 |
| US-20110218142-A1 | Inhibitors of Dipeptidylpeptidase IV | DPP4, DPP3, DPP7 | DPP9 8/4885DPP4 1/4885DPP8 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.