Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | EEF2K | O00418 | 2/20 | 0.39 |
| ▸ | EEF2 | P13639 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18840270 | 0.98 | CYP2D6 (0.46) | CYP2D6TBXAS1TLR8NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL30212798 | 0.94 | TLR8 (0.42) | CYP2D6TBXAS1TLR8NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL30213064 | 0.93 | CYP2D6 (0.41) | CYP2D6TBXAS1TLR8NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL30213000 | 0.93 | CYP2D6 (0.41) | CYP2D6TBXAS1TLR8NPC1RAB9A | |
| Fluoride SCHEMBL30330580 | 0.93 | CYP2D6 (0.41) | CYP2D6TBXAS1TLR8NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL30212630 | 0.93 | CYP2D6 (0.41) | CYP2D6TBXAS1TLR8NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL30212797 | 0.93 | CYP2D6 (0.41) | CYP2D6TBXAS1TLR8NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL30212741 | 0.93 | CYP2D6 (0.41) | CYP2D6TBXAS1TLR8NPC1RAB9A | |
| Fluoride SCHEMBL30330927 | 0.93 | CYP2D6 (0.41) | CYP2D6TBXAS1TLR8NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL30212651 | 0.93 | CYP2D6 (0.41) | CYP2D6TBXAS1TLR8NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487870-B1 | Insecticidal and acaricidal diarylpyrrolecarbonitrile and diarylnitropyrrole compounds | AMERICAN CYANAMID CO (US) | 1996-12-18 | — | — | EP | claimed |
| US-5233052-A | Insecticidal and acaricidal diarylpyrrolecarbonitrile and diarylnitropyrrole compounds | AMERICAN CYANAMID COMPANY (US) | 1993-08-03 | — | — | US | claimed |
| EP-0487870-A2 | Insecticidal and acaricidal diarylpyrrolecarbonitrile and diarylnitropyrrole compounds | AMERICAN CYANAMID COMPANY (US) | 1992-06-03 | — | — | EP | claimed |
| EP-0146411-B1 | PHOTOSOLUBILISABLE COMPOSITIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-07-31 | — | — | EP | claimed |
| US-4708925-A | PRINTING PLATES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-11-24 | — | — | US | claimed |
| EP-0146411-A2 | Photosolubilisable compositions | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1985-06-26 | — | — | EP | claimed |
| EP-2277124-B1 | MEANS FOR TREATING MYOSIN-RELATED DISEASES | HANNOVER MED HOCHSCHULE (DE) | 2016-11-09 | — | — | EP | disclosed |
| EP-1739485-B1 | RESIST COMPOSITION | MITSUBISHI GAS CHEMICAL CO (JP) | 2016-08-31 | — | — | EP | disclosed |
| EP-2581451-B1 | Compounds for inhibiting mammalian s-nitrosoglutathione reductase | UNIV INDIANA RES & TECH CORP (US) | 2016-03-09 | — | — | EP | disclosed |
| EP-2614050-B1 | 1,5-DIARYL-2-ALKYLPYRROLE-3-SUBSTITUTED NITRO ESTERS, SELECTIVE COX-2 INHIBITORS AND NITRIC OXIDE DONORS | Rottapharm Biotech Srl (IT) | 2016-01-20 | — | — | EP | disclosed |
| US-9198909-B1 | Materials and methods for inhibiting mamalian S-nitrosoglutathione reductase | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2015-12-01 | — | — | US | disclosed |
| US-9162979-B2 | 1,5-Diary1-2-alkylpyrrole-3-substituted nitro esters, selective COX-2 inhibitors and nitric oxide donors | ROTTAPHARM BIOTECH S.R.L. (IT) | 2015-10-20 | — | — | US | disclosed |
| EP-2059504-B1 | 3-SUBSTITUTED-1,5-DIARLY-2-ALKYL-PYRROLES HIGHLY SELECTIVE AND ORALLY EFFECTIVE COX-2 INHIBITORS | Rottapharm Biotech Srl (IT) | 2015-09-09 | — | — | EP | disclosed |
| US-4652582-A | ANALGESICS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-03-24 | — | — | US | disclosed |
| EP-0146411-A2 | Photosolubilisable compositions | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1985-06-26 | — | — | EP | disclosed |
| EP-0034798-B1 | ANTIINFLAMMATORY 4,5-DIARYL-2-(SUBSTITUTED-THIO)PYRROLES AND THEIR CORRESPONDING SULFOXIDES AND SULFONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-05-22 | — | — | EP | disclosed |
| EP-0005156-B1 | 4,5-DIARYL-2-(SUBSTITUTED-THIO)-PYRROLES AND THEIR CORRESPONDING SULFOXIDES AND SULFONES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-09-22 | — | — | EP | disclosed |
| EP-0034798-A2 | Antiinflammatory 4,5-diaryl-2-(substituted-thio)pyrroles and their corresponding sulfoxides and sulfones | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-09-02 | — | — | EP | disclosed |
| US-4267184-A | USEFUL FOR TREATING ARTHRITIS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-05-12 | — | — | US | disclosed |
| EP-0005156-A1 | 4,5-diaryl-2-(substituted-thio)-pyrroles and their corresponding sulfoxides and sulfones, process for their preparation and pharmaceutical compositions containing them | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-11-14 | — | — | EP | disclosed |