Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 16/20 | 0.53 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.52 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.52 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | PREP | P48147 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3741673 | 0.83 | DPP4 (0.49) | DPP4DPP8DPP9DPP7PREP | |
| SCHEMBL6358538 | 0.83 | DPP4 (0.61) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL6358540 | 0.83 | DPP4 (0.61) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL8250574 | 0.80 | DPP4 (0.54) | DPP4DPP8DPP9DPP7PREP | |
| SCHEMBL6358516 | 0.79 | AAK1 (0.42) | PREP | |
| SCHEMBL6358515 | 0.79 | AAK1 (0.42) | PREP | |
| SCHEMBL6360005 | 0.79 | AAK1 (0.42) | PREP | |
| SCHEMBL6358520 | 0.79 | AAK1 (0.42) | PREP | |
| SCHEMBL6359604 | 0.77 | PREP (0.65) | DPP4DPP8DPP9DPP7PREP | |
| SCHEMBL6359606 | 0.77 | PREP (0.65) | DPP4DPP8DPP9DPP7PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005100334-A1 | DIPEPTIDYL PEPTIDASE-IV INHIBITORS | PFIZER PRODUCTS INC. (US) | 2005-10-27 | — | — | WO | disclosed |