Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13460092 | 1.00 | CYP1A2 (0.52) | CYP1A2SIGMAR1OPRK1METAP1MAPT | |
| SCHEMBL8280560 | 0.94 | CYP1A2 (0.50) | CYP1A2SIGMAR1OPRK1METAP1MAPT | |
| SCHEMBL8281786 | 0.93 | CYP1A2 (0.43) | CYP1A2SIGMAR1OPRK1MAPT | |
| SCHEMBL8281751 | 0.91 | CYP1A2 (0.46) | CYP1A2SIGMAR1OPRK1METAP1MAPT | |
| SCHEMBL25791600 | 0.86 | CYP1A2 (0.44) | CYP1A2SIGMAR1METAP1 | |
| SCHEMBL8282831 | 0.86 | CYP1A2 (0.44) | CYP1A2SIGMAR1METAP1 | |
| SCHEMBL1524631 | 0.82 | CYP1A2 (0.56) | CYP1A2SIGMAR1OPRK1METAP1MAPT | |
| SCHEMBL13460091 | 0.82 | MAPT (0.37) | CYP1A2SIGMAR1MAPT | |
| SCHEMBL9253751 | 0.82 | CYP1A2 (0.56) | CYP1A2SIGMAR1OPRK1METAP1MAPT | |
| SCHEMBL9379793 | 0.79 | CYP1A2 (0.52) | CYP1A2SIGMAR1OPRK1METAP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005070916-A1 | THIOPHENE AND FURAN COMPOUNDS | ELI LILLY AND COMPANY (US) | 2005-08-04 | — | — | WO | disclosed |