SCHEMBL828176

SCHEMBL828176

ON1Nc2ccccc2S1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
POLB P06746 2/20 0.39
ALOX15 P16050 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
MAPT P10636 2/20 0.39
NOX1 Q9Y5S8 2/20 0.39
CYP1A2 P05177 1/20 0.39
BCHE P06276 1/20 0.39
CYP3A4 P08684 1/20 0.39
ADORA3 P0DMS8 1/20 0.39
ALOX12 P18054 1/20 0.39
MAOA P21397 1/20 0.39
CNR1 P21554 1/20 0.39
ACHE P22303 1/20 0.39
PTGS1 P23219 1/20 0.39
SLC6A2 P23975 1/20 0.39
HTR2C P28335 1/20 0.39
PTGS2 P35354 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26216995 0.73 GAA (0.39) GAAMEN1KMT2APOLBALOX15
SCHEMBL134753 0.73 GAA (0.39) GAAMEN1KMT2APOLBALOX15
SCHEMBL11382715 0.73 GAA (0.39) GAAMEN1KMT2APOLBALOX15
SCHEMBL10497258 0.73 GAA (0.39) GAAMEN1KMT2APOLBALOX15
SCHEMBL11382719 0.73 NOX1 (0.39) GAAMEN1KMT2APOLBALOX15
SCHEMBL28387095 0.71 GAA (0.38) GAAMEN1KMT2APOLBALOX15
SCHEMBL15065849 0.69 MEN1 (0.36) GAAMEN1KMT2APOLBALOX15
SCHEMBL17433706 0.68 NOX1 (0.35) GAAMEN1KMT2APOLBALOX15
SCHEMBL1766174 0.66 SNCA (0.38) GAAMEN1KMT2APOLBALOX15
SCHEMBL16516017 0.65 POLB (0.32) GAAMEN1KMT2APOLBALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8143011-B2 MAGE-C2 antigenic peptides and uses thereof LUDWIG INSTITUTE FOR CANCER RESEARCH (US) 2012-03-27 US disclosed
US-20110305722-A1 MAGE-C2 ANTIGENIC PEPTIDES AND USES THEREOF MA WENBIN (BE) 2011-12-15 US disclosed
US-7785881-B2 MAGE-C2 antigenic peptides and uses thereof LUDWIG INSTITUTE FOR CANCER RESEARCH (US) 2010-08-31 US disclosed
US-20090233315-A1 MAGE-C2 antigenic peptides and uses therefor MA WENBIN 2009-09-17 US disclosed
US-20080311652-A1 MAGE-C2 antigenic peptides and uses thereof PEL ALINE VAN 2008-12-18 US disclosed