Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.54 |
| ▸ | CTSV | O60911 | 1/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.54 |
| ▸ | CTSB | P07858 | 1/20 | 0.54 |
| ▸ | CMA1 | P23946 | 1/20 | 0.54 |
| ▸ | CTSS | P25774 | 1/20 | 0.54 |
| ▸ | CTSK | P43235 | 1/20 | 0.54 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP4 | P49662 | 1/20 | 0.40 |
| ▸ | CASP5 | P51878 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | CASP9 | P55211 | 1/20 | 0.40 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.40 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8283743 | 0.97 | ELANE (0.57) | ELANECTSVCTSLCTSBCMA1 | |
| SCHEMBL12605574 | 0.91 | ELANE (0.65) | ELANECTSVCTSLCTSBCMA1 | |
| SCHEMBL12605573 | 0.89 | CMA1 (0.50) | ELANECTSVCTSLCTSBCMA1 | |
| SCHEMBL12605542 | 0.88 | ELANE (0.59) | ELANECTSVCTSLCTSBCMA1 | |
| SCHEMBL12605544 | 0.88 | ELANE (0.69) | ELANECTSVCTSLCTSBCMA1 | |
| SCHEMBL12605563 | 0.88 | ELANE (0.69) | ELANECTSVCTSLCTSBCMA1 | |
| SCHEMBL12698660 | 0.88 | ELANE (0.69) | ELANECTSVCTSLCTSBCMA1 | |
| SCHEMBL16329103 | 0.88 | ELANE (0.59) | ELANECTSVCTSLCTSBCMA1 | |
| SCHEMBL12600879 | 0.88 | ELANE (0.54) | ELANECTSVCTSLCTSBCMA1 | |
| SCHEMBL8253104 | 0.87 | ELANE (0.47) | ELANECTSVCTSLCTSBCMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005085242-A1 | NOVEL KETOAMIDES WITH CYCLIC P4'S AS INHIBITORS OF NS3 SERINE PROTEASE OF HEPATITIS C VIRUS | SCHERING CORPORATION (US) | 2005-09-15 | — | — | WO | disclosed |