Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8283519 | 0.87 | BACE1 (0.48) | BACE1CTSD | |
| SCHEMBL8281560 | 0.87 | BACE1 (0.64) | BACE1CTSD | |
| SCHEMBL8281846 | 0.85 | BACE1 (0.49) | BACE1CTSD | |
| SCHEMBL8282555 | 0.84 | BACE1 (0.64) | BACE1CTSD | |
| SCHEMBL8283445 | 0.82 | BACE1 (0.48) | BACE1CTSD | |
| SCHEMBL2873462 | 0.82 | BACE1 (0.48) | BACE1CTSD | |
| SCHEMBL8282610 | 0.82 | BACE1 (0.51) | BACE1CTSD | |
| SCHEMBL8281826 | 0.81 | BACE1 (0.61) | BACE1CTSD | |
| SCHEMBL2879615 | 0.78 | BACE1 (0.64) | BACE1CTSD | |
| SCHEMBL8281521 | 0.78 | BACE1 (0.64) | BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005070407-A1 | METHODS OF TREATMENT OF AMYLOIDOSIS USING ASPARTYL-PROTEASE INIHIBITORS | ELAN PHARMACEUTICALS, INC. (US) | 2005-08-04 | — | — | WO | disclosed |