⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13929441 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL31340197 | 0.66 | MAP2K1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL31340325 | 0.66 | MAP2K1 (0.31) | — | |
| SCHEMBL14811210 | 0.64 | — | — | |
| SCHEMBL1259103 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL3904928 | 0.60 | — | — | |
| SCHEMBL8290501 | 0.60 | — | — | |
| SCHEMBL14185497 | 0.60 | GABRR1 (0.36) | — | |
| SCHEMBL6685991 | 0.59 | — | — | |
| SCHEMBL405604 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9839664-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2017-12-12 | — | — | US | disclosed |
| US-20170216392-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS LLC | 2017-08-03 | — | — | US | disclosed |
| US-8168655-B2 | Compositions and methods for treatment of eye disorders | SARCODE BIOSCIENCE INC. (US) | 2012-05-01 | — | — | US | disclosed |
| EP-1682537-B1 | MODULATORS OF CELLULAR ADHESION | SARCODE BIOSCIENCE INC (US) | 2012-03-28 | — | — | EP | disclosed |
| WO-2005063764-A2 | FUSED PYRROLOCARBAZOLES AND METHODS FOR THE PREPARATION THEREOF | CEPHALON, INC. (US) | 2005-07-14 | — | — | WO | disclosed |