Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.44 |
| ▸ | MAPT | P10636 | 9/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | RAB9A | P51151 | 8/20 | 0.44 |
| ▸ | HTT | P42858 | 7/20 | 0.44 |
| ▸ | LMNA | P02545 | 7/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6462240 | 0.87 | F10 (0.46) | F10SMN1; SMN2MAPTALDH1A1RAB9A | |
| SCHEMBL6457967 | 0.81 | NPC1 (0.46) | F10SMN1; SMN2MAPTALDH1A1RAB9A | |
| SCHEMBL4465226 | 0.79 | F10 (0.58) | F10SMN1; SMN2MAPTALDH1A1RAB9A | |
| SCHEMBL4463938 | 0.79 | F10 (0.58) | F10SMN1; SMN2MAPTALDH1A1RAB9A | |
| SCHEMBL6457978 | 0.78 | F10 (0.46) | F10SMN1; SMN2MAPTALDH1A1RAB9A | |
| SCHEMBL4465515 | 0.78 | F10 (0.48) | F10SMN1; SMN2MAPTALDH1A1RAB9A | |
| SCHEMBL6459518 | 0.78 | F10 (0.48) | F10SMN1; SMN2MAPTALDH1A1RAB9A | |
| SCHEMBL4463507 | 0.78 | F10 (0.68) | F10CTSLCTSBCTSS | |
| SCHEMBL4479375 | 0.78 | F10 (0.57) | F10SMN1; SMN2MAPTALDH1A1RAB9A | |
| SCHEMBL4471694 | 0.78 | F10 (0.68) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005111013-A1 | SUBSTITUTED THIOPHENE-2-CARBOXYLIC ACID AMIDES, THE PRODUCTION THEREOF AND THE USE THEREOF AS DRUGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-24 | — | — | WO | disclosed |