Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 16/20 | 0.55 |
| ▸ | FAP | Q12884 | 12/20 | 0.53 |
| ▸ | DPP9 | Q86TI2 | 8/20 | 0.53 |
| ▸ | DPP8 | Q6V1X1 | 8/20 | 0.53 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.53 |
| ▸ | PREP | P48147 | 7/20 | 0.50 |
| ▸ | PITRM1 | Q5JRX3 | 3/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13347240 | 0.89 | DPP4 (0.57) | DPP4FAPDPP9DPP8DPP7 | |
| SCHEMBL8288240 | 0.77 | DPP4 (0.55) | DPP4FAPDPP9DPP8DPP7 | |
| SCHEMBL16104916 | 0.73 | HPGD (0.46) | DPP4DPP8 | |
| SCHEMBL8234730 | 0.71 | DPP4 (1.00) | DPP4FAPDPP9DPP8DPP7 | |
| SCHEMBL4417766 | 0.71 | DPP4 (1.00) | DPP4FAPDPP9DPP8DPP7 | |
| SCHEMBL8285601 | 0.70 | DPP4 (0.70) | DPP4FAPDPP9DPP8DPP7 | |
| SCHEMBL13347244 | 0.70 | DPP4 (0.70) | DPP4FAPDPP9DPP8DPP7 | |
| SCHEMBL13347238 | 0.70 | DPP4 (0.49) | DPP4FAPDPP9DPP8DPP7 | |
| SCHEMBL16104907 | 0.70 | DPP4 (0.67) | DPP4FAPDPP9DPP8DPP7 | |
| SCHEMBL3179037 | 0.70 | DPP4 (0.67) | DPP4FAPDPP9DPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005047297-A1 | HETEROCYCLIC BORONIC ACID COMPOUNDS | PHENOMIX CORPORATION (US) | 2005-05-26 | — | — | WO | disclosed |