Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8286703 | 0.89 | BACE1 (0.82) | BACE1BACE2 | |
| SCHEMBL12993760 | 0.88 | BACE1 (0.84) | BACE1BACE2 | |
| SCHEMBL3603433 | 0.87 | BACE1 (0.79) | BACE1BACE2 | |
| SCHEMBL3603429 | 0.87 | BACE1 (0.79) | BACE1BACE2 | |
| SCHEMBL8284893 | 0.87 | BACE1 (0.81) | BACE1BACE2 | |
| SCHEMBL8284924 | 0.87 | BACE1 (0.81) | BACE1BACE2 | |
| SCHEMBL8284178 | 0.86 | BACE1 (0.80) | BACE1BACE2 | |
| SCHEMBL8285867 | 0.85 | BACE1 (1.00) | BACE1BACE2 | |
| SCHEMBL8284957 | 0.84 | BACE1 (0.75) | BACE1BACE2 | |
| SCHEMBL3588803 | 0.84 | BACE1 (0.77) | BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005103020-A1 | 1,3,5-SUBSTITUTED PHENYL DERIVATIVE COMPOUNDS USEFUL AS BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | MERCK & CO., INC. (US) | 2005-11-03 | — | — | WO | disclosed |