Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | F9 | P00740 | 1/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4627767 | 0.92 | F10 (0.46) | F10F2F9PLATKLKB1 | |
| SCHEMBL4627765 | 0.92 | F10 (0.46) | F10F2F9PLATKLKB1 | |
| SCHEMBL4627153 | 0.90 | F10 (0.59) | F10F2F9PLATKLKB1 | |
| SCHEMBL4626069 | 0.90 | F10 (0.58) | F10F2F9PLATKLKB1 | |
| SCHEMBL4627738 | 0.90 | F10 (0.58) | F10F2F9PLATKLKB1 | |
| SCHEMBL4627771 | 0.89 | F10 (0.46) | F10F2F9PLATKLKB1 | |
| SCHEMBL4627769 | 0.89 | F10 (0.46) | F10F2F9PLATKLKB1 | |
| SCHEMBL4626266 | 0.87 | F10 (0.56) | F10F2F9PLATKLKB1 | |
| SCHEMBL4626260 | 0.87 | F10 (0.56) | F10F2F9PLATKLKB1 | |
| SCHEMBL4625773 | 0.87 | F10 (0.55) | F10F2F9PLATKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005048922-A2 | SULFONYLAMINOVALEROLACTAMS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-06-02 | — | — | WO | disclosed |