Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 12/20 | 0.53 |
| ▸ | KDM5A | P29375 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | GLP1R | P43220 | 2/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12226819 | 0.91 | CSF1R (0.50) | CSF1RALDH1A1HTT | |
| SCHEMBL8283857 | 0.87 | CSF1R (0.57) | CSF1RALDH1A1POLBHTT | |
| SCHEMBL8283854 | 0.85 | CSF1R (0.53) | CSF1RALDH1A1POLBHTT | |
| SCHEMBL8286204 | 0.84 | CSF1R (0.50) | CSF1RALDH1A1POLBHTT | |
| SCHEMBL8286215 | 0.81 | CSF1R (0.57) | CSF1RALDH1A1POLBHTT | |
| SCHEMBL8284698 | 0.81 | CDK1 (0.42) | ALDH1A1HTT | |
| SCHEMBL12884198 | 0.79 | CSF1R (0.42) | CSF1RHTT | |
| SCHEMBL8286225 | 0.79 | CSF1R (0.53) | CSF1RALDH1A1POLBHTT | |
| SCHEMBL12884197 | 0.78 | CSF1R (0.39) | CSF1RALDH1A1POLBHTT | |
| SCHEMBL12884202 | 0.78 | CSF1R (0.43) | CSF1RHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005058869-A1 | AMINOBENZIMIDAZOLES AND BENZIMIDAZOLES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2005-06-30 | — | — | WO | disclosed |