Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 17/20 | 0.45 |
| ▸ | PREP | P48147 | 2/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5646118 | 0.83 | DPP4 (0.62) | DPP4PREPDPP8DPP9 | |
| SCHEMBL5649234 | 0.77 | DPP4 (0.52) | DPP4PREPDPP8DPP9 | |
| SCHEMBL5649172 | 0.75 | DPP4 (0.47) | DPP4PREPDPP8DPP9 | |
| SCHEMBL14602195 | 0.75 | DPP4 (0.56) | DPP4PREPDPP8DPP9 | |
| SCHEMBL5646012 | 0.75 | DPP4 (0.56) | DPP4PREPDPP8DPP9 | |
| SCHEMBL8284353 | 0.75 | DPP4 (0.59) | DPP4DPP8DPP9 | |
| SCHEMBL8286010 | 0.75 | DPP4 (0.59) | DPP4DPP8DPP9 | |
| SCHEMBL14602200 | 0.73 | DPP4 (0.45) | DPP4PREPDPP8DPP9 | |
| SCHEMBL8286261 | 0.70 | DPP4 (0.60) | DPP4PREPDPP8DPP9 | |
| SCHEMBL8284342 | 0.70 | DPP4 (0.60) | DPP4PREPDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005058849-A1 | NEW DIPEPTIDYL PEPTIDASE IN INHIBITORS; PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LTD. (US) | 2005-06-30 | — | — | WO | disclosed |