SCHEMBL8288153

SCHEMBL8288153

Oc1ccc(C2CC=CCC2)cc1

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 20/20 0.50
ESR1 P03372 7/20 0.46
CYP3A4 P08684 2/20 0.46
CYP2C9 P11712 2/20 0.46
MEN1 O00255 1/20 0.45
ALDH1A1 P00352 1/20 0.45
MAPT P10636 1/20 0.45
ALOX15 P16050 1/20 0.45
HTT P42858 1/20 0.45
KMT2A Q03164 1/20 0.45
HSD17B10 Q99714 1/20 0.45
CYP2D6 P10635 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18726005 0.84 ESR2 (0.54) ESR2ESR1CYP3A4CYP2C9MEN1
SCHEMBL6399792 0.82 SLC6A4 (0.43) ESR2ESR1CYP3A4CYP2C9MEN1
SCHEMBL29557795 0.79 KDM1A (0.38) ALDH1A1CYP2D6
SCHEMBL29557451 0.79 SLC18A3 (0.38) ALDH1A1MAPTHTTCYP2D6
SCHEMBL29558540 0.79 SLC6A2 (0.55) MEN1ALDH1A1HTTKMT2AHSD17B10
SCHEMBL35975 0.78 SLC18A3 (0.45) MAPTHSD17B10CYP2D6
SCHEMBL29557767 0.78 SLC18A3 (0.45) MAPTHSD17B10CYP2D6
SCHEMBL4357328 0.77 TSHR (0.43) ALDH1A1ALOX15
Bicarbonate SCHEMBL11313316 0.76 AKR1C3 (0.46) MEN1ALDH1A1MAPTHTTKMT2A
SCHEMBL5704310 0.76 ESR2 (0.61) ESR2ESR1CYP3A4CYP2C9CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103827221-B Resin composition, resin sheet, resin sheet cured product, metal foil with resin, and heat dissipation member 日立化成株式会社 2017-05-03 CN disclosed
CN-101033293-B Polyfunctional phenylene ether oligomer, derivative thereof, resin composition containing the same, and use thereof MITSUBISHI GAS CHEMICAL CO 2011-11-16 CN disclosed
CN-101033293-A Polyfunctional phenylene ether oligomer, derivative thereof, resin composition containing the same, and use thereof MITSUBISHI GAS CHEMICAL CO (JP) 2007-09-12 CN disclosed
WO-2005058298-A2 FK228 ANALOGS AND THEIR USE AS HDAC-INHIBITORS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2005-06-30 WO disclosed
US-4189613-A OF PHENOLS WITH SELECTIVE CHROMIA ON ALUMINA CATALYST PHILLIPS PETROLEUM COMPANY (US) 1980-02-19 US disclosed