Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 1.00 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.68 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.68 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8290072 | 1.00 | DPP4 (1.00) | DPP4DPP8DPP9DPP7CYP2D6 | |
| SCHEMBL14421718 | 0.90 | DPP4 (0.81) | DPP4DPP8DPP9DPP7CYP2D6 | |
| SCHEMBL8289055 | 0.90 | DPP4 (1.00) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL8288995 | 0.90 | DPP4 (1.00) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL23752266 | 0.90 | DPP4 (1.00) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL4956172 | 0.87 | DPP4 (0.94) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL8288179 | 0.87 | DPP4 (1.00) | DPP4DPP8DPP9DPP7CYP2D6 | |
| SCHEMBL8288180 | 0.86 | DPP4 (1.00) | DPP4DPP8DPP9DPP7CYP2D6 | |
| SCHEMBL14421652 | 0.86 | DPP4 (1.00) | DPP4DPP8DPP9DPP7CYP2D6 | |
| SCHEMBL8289047 | 0.84 | DPP4 (0.80) | DPP4DPP8DPP9DPP7CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005056003-A1 | DPP-IV INHIBITORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) GMBH (CH) | 2005-06-23 | — | — | WO | disclosed |