Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 15/20 | 0.69 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.50 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1886609 | 0.82 | HDAC1 (1.00) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL6509553 | 0.81 | HDAC1 (0.78) | HDAC1RAB9AHDAC6HDAC3HDAC4 | |
| SCHEMBL6512704 | 0.80 | HDAC1 (0.76) | HDAC1RAB9AKCNK3HDAC6HDAC3 | |
| SCHEMBL6511964 | 0.80 | HDAC1 (0.76) | HDAC1RAB9AHDAC6HDAC3HDAC4 | |
| SCHEMBL22718544 | 0.79 | HDAC1 (0.74) | HDAC1KCNK9HDAC6HDAC3HDAC11 | |
| SCHEMBL6514967 | 0.79 | HDAC1 (0.74) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL6510390 | 0.78 | HDAC1 (0.77) | HDAC1RAB9AHDAC6HDAC3HDAC4 | |
| SCHEMBL6515331 | 0.78 | HDAC1 (0.77) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL8286988 | 0.78 | HDAC1 (0.65) | HDAC1RAB9A | |
| SCHEMBL1894177 | 0.78 | HDAC1 (0.85) | HDAC1HDAC6HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005066151-A2 | HISTONE DEACETYLASE INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2005-07-21 | — | — | WO | disclosed |