Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 10/20 | 0.64 |
| ▸ | S1PR4 | O95977 | 7/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10227870 | 0.88 | MRGPRX4 (0.53) | MRGPRX4S1PR4LMNAMAPTGAA | |
| SCHEMBL29963026 | 0.86 | SYK (0.50) | MRGPRX4S1PR4LMNAMAPTGAA | |
| SCHEMBL1016955 | 0.86 | SYK (0.50) | MRGPRX4S1PR4LMNAMAPTGAA | |
| SCHEMBL15701539 | 0.83 | MRGPRX4 (0.53) | MRGPRX4S1PR4LMNAMAPTGAA | |
| SCHEMBL22225187 | 0.83 | MRGPRX4 (0.46) | MRGPRX4S1PR4LMNAMAPTGAA | |
| SCHEMBL29826138 | 0.82 | MRGPRX4 (0.64) | MRGPRX4S1PR4MAPTTDP1NPC1 | |
| SCHEMBL1015664 | 0.80 | MAPT (0.53) | MRGPRX4S1PR4LMNAMAPTNPC1 | |
| SCHEMBL22480865 | 0.78 | MRGPRX4 (1.00) | MRGPRX4 | |
| SCHEMBL2252935 | 0.77 | MRGPRX4 (0.41) | MRGPRX4S1PR4NPC1 | |
| SCHEMBL15932884 | 0.76 | NPC1 (0.53) | MRGPRX4S1PR4LMNAMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005044265-A1 | ALKYNES III | ASTRAZENECA AB (SE) | 2005-05-19 | — | — | WO | disclosed |