Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 13/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 13/20 | 0.65 |
| ▸ | MAPT | P10636 | 8/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.65 |
| ▸ | POLB | P06746 | 8/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | RECQL | P46063 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | DUSP22 | Q9NRW4 | 4/20 | 0.51 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3907485 | 0.85 | MEN1 (0.67) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL3907489 | 0.85 | MEN1 (0.67) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL3895634 | 0.84 | POLB (0.72) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL3895627 | 0.84 | POLB (0.72) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL15374280 | 0.84 | POLB (0.72) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL3892524 | 0.81 | MEN1 (0.60) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL3892527 | 0.81 | MEN1 (0.60) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL22108635 | 0.81 | MEN1 (0.60) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL3012532 | 0.79 | MEN1 (1.00) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL3895640 | 0.79 | MAP3K5 (0.64) | MEN1KMT2AMAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005041951-A2 | RHODANINE DERIVATIVES FOR USE AS ANTIVIRAL AGENTS | RIGEL PHARMACEUTICALS, INC. (US) | 2005-05-12 | — | — | WO | disclosed |