Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 14/20 | 1.00 |
| ▸ | NPC1 | O15118 | 7/20 | 0.81 |
| ▸ | RAB9A | P51151 | 7/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.81 |
| ▸ | MEN1 | O00255 | 4/20 | 0.81 |
| ▸ | POLB | P06746 | 2/20 | 0.81 |
| ▸ | CASP3 | P42574 | 1/20 | 0.72 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | CFTR | P13569 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8289839 | 0.99 | FLT3 (0.98) | FLT3NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL8289830 | 0.98 | FLT3 (0.95) | FLT3NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL5457413 | 0.88 | FLT3 (0.79) | FLT3NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL8288698 | 0.88 | FLT3 (0.79) | FLT3NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL5455846 | 0.87 | FLT3 (1.00) | FLT3NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL3128198 | 0.87 | FLT3 (1.00) | FLT3NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL8289672 | 0.85 | FLT3 (0.97) | FLT3NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL8290663 | 0.85 | FLT3 (1.00) | FLT3NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL8289414 | 0.85 | FLT3 (0.96) | FLT3NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL22789481 | 0.84 | FLT3 (0.75) | FLT3NPC1RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033102-A2 | THIOPHENE-BASED COMPOUNDS EXHIBITING ATP-UTILIZING ENZYME INHIBITORY ACTIVITY, AND COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORPORATION (US) | 2005-04-14 | — | — | WO | disclosed |